Integumentary System Crossword Puzzle

A themed crossword with 38 clues to draw from. Find terms for skin, its layers and glands, plus hair, nails, and the body’s protective functions.

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About the Integumentary System Crossword Puzzle

This puzzle covers the integumentary system: skin and its layers, hair and nails, glands, pigments, and protective functions. Look for terms such as Epidermis, Keratin, Sebaceous Gland, and Sunburn. It is suited to students reviewing human anatomy and anyone curious about how the body protects itself, senses touch, and helps regulate temperature.

This crossword draws on 38 clues about Integumentary System. Each grid uses a different handful and fits them together a new way, so press New puzzle for another whenever you finish. The answers are in the answer key when you print, and behind the Reveal button when you play.

Sample clues

  • •Scent-producing secretion structure (13 letters)
  • •Strong structural protein in connective tissue (8 letters)
  • •Cooling-fluid-producing structure (12 letters)
  • •Small spot often darkened by sunlight (7 letters)
  • •Deep layer beneath the dermis (10 letters)
  • •Small dark spot on the body (4 letters)
  • •Coloring substance in tissue (7 letters)
  • •Mark left after an injury heals (4 letters)

Teaching this topic or planning a party? Make your own crossword with your own words and clues.

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